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EVALUATION OF SENSITIVITY TO CLOPIDOGREL: THE CURRENT STATE OF THE PROBLEM

Atherothrombosis Journal

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Title EVALUATION OF SENSITIVITY TO CLOPIDOGREL: THE CURRENT STATE OF THE PROBLEM
ОЦЕНКА ЧУВСТВИТЕЛЬНОСТИ К КЛОПИДОГРЕЛУ: СОВРЕМЕННОЕ СОСТОЯНИЕ ПРОБЛЕМЫ
 
Creator A. Komarov L.; Russian Cardiology Research and Production Complex of the Ministry of Health of the Russian Federation, Moscow, Russia
А. КОМАРОВ Л.; ФГБУ «Российский кардиологический научно-производственный комплекс» Министерства здравоохранения РФ, Москва
 
Subject —
фармакогенетика;остаточная реактивность тромбоцитов к АДФ;антиагрегантная терапия;чрескожные коронарные вмешательства;тромбоз
 
Description The review deals with the laboratory assessment of clopidogrel effect in patients with CHD. The article presents the results of major studies that have demonstrated the relationship between the residual platelet reactivity level and drug pharmacogenetics abnormalities causing coronary complications. It discusses proposals of the international expert organizations on the assessment of sensitivity to clopidogrel and possible modifications of antiplatelet treatment.
Обзор посвящен лабораторной оценке действия клопидогрела у ИБС. Приведены результаты основных крупных исследований, продемонстрировавших связь уровня остаточной реактивности тромбоцитов и нарушений фармакогенетики препарата с развитием ишемических осложнений. Рассмотрены предложения международных экспертных организаций по оценке чувствительности к клопи-догрелу и возможной модификации антитромбоцитарного лечения.
 
Publisher «REMEDIUM GROUP» Ltd.
 
Contributor —
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Date 2016-05-31
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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Format application/pdf
 
Identifier http://www.aterotromboz.ru/jour/article/view/52
10.21518/2307-1109-2015-2-95-106
 
Source Atherothrombosis Journal; № 2 (2015); 95-106
Атеротромбоз; № 2 (2015); 95-106
2307-1109
10.21518/2307-1109-2015-2
 
Language rus
 
Relation http://www.aterotromboz.ru/jour/article/view/52/78
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