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Kidney transplantation and bone disease: risk factors of development and diagnostics

Russian Journal of Transplantology and Artificial Organs

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Title Kidney transplantation and bone disease: risk factors of development and diagnostics
Трансплантация почки и костная болезнь: факторы риска развития, диагностика
 
Creator O. Vetchinnikova N.; M.F. Vladimirsky Moscow Regional Clinical and Research Institute
О. Ветчинникова Н.; ГБУЗ МО «Московский областной научно-исследовательский клинический институт имени М.Ф. Владимирского»
 
Subject kidney transplantation; post-transplant bone disease
трансплантация почки;посттрансплантационная костная болезнь
 
Description Bone disease is a serious and common condition in patients after kidney transplantation. The review analyzed the causes of bone disorders in the early and late postoperative period that are associated with renal transplantation: fibroblast growth factor 23, parathyroid hormone, vitamin D, immunosuppressive therapy and imbalance of mineral metabolism. It shows the most common clinical variant of the post-transplant bone disease – secondary osteoporosis, risk factors of its development and complications. It presents the diagnostic algorithm for dynamic monitoring and evaluating the effectiveness of the treatment of bone disorders
Заболевание костей является серьезной и часто встречающейся патологией у пациентов, перенесших трансплантацию почки. Рассмотрены разнообразные связанные с трансплантацией почки причины возникновения костных нарушений в раннем и отдаленном послеоперационном периоде: дисбаланс гормонов – фактора роста фибробластов 23, паратиреоидного гормона, витамина D, – иммуносупрессивная терапия, нарушение минерального обмена. Описан наиболее распространенный клинический вариант течения посттрансплантационной костной болезни – вторичный остеопороз, факторы риска его развития и осложнения. Анализируется диагностический алгоритм для выявления, динамического наблюдения и оценки эффективности проводимого лечения костных нарушений.
 
Publisher V.I.Shumakov Federal Research Center of Transplantology and Artificial Organs
 
Contributor —
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Date 2017-04-14
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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Format application/pdf
 
Identifier http://journal.transpl.ru/vtio/article/view/740
10.15825/1995-1191-2017-1-111-121
 
Source Russian Journal of Transplantology and Artificial Organs; Том 19, № 1 (2017); 111-121
Вестник трансплантологии и искусственных органов; Том 19, № 1 (2017); 111-121
2412-6160
1995-1191
10.15825/1995-1191-2017-1
 
Language rus
 
Relation http://journal.transpl.ru/vtio/article/view/740/618
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