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Pathophysiological Aspects of Hyperoxia in Anesthesiologist-Reanimatologist's Practice

General Reanimatology

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Title Pathophysiological Aspects of Hyperoxia in Anesthesiologist-Reanimatologist's Practice
Патофизиологические аспекты гипероксии в практике анестезиолога реаниматолога (мини-обзор)
 
Creator Vladimir Dolgikh T.; Omsk State Medical University, Ministry of Health of Russia
Natalia Govorova V.; Omsk State Medical University, Ministry of Health of Russia
Yury Orlov P.; Omsk State Medical University, Ministry of Health of Russia
Olga Korpacheva V.; Omsk State Medical University, Ministry of Health of Russia
Galina Dorovskikh N.; Omsk State Medical University, Ministry of Health of Russia
Anton Ershov V.; Omsk State Medical University, Ministry of Health of Russia
В. Долгих Т.; Омский государственный медицинский университет Минздрава России
Н. Говорова В.; Омский государственный медицинский университет Минздрава России
Ю. Орлов П.; Омский государственный медицинский университет Минздрава России
О. Корпачева В.; Омский государственный медицинский университет Минздрава России
Г. Доровских Н.; Омский государственный медицинский университет Минздрава России
А. Ершов В.; Омский государственный медицинский университет Минздрава России
 
Subject hypoxia; hyperoxia; succinates
гипоксия; гипероксия; сукцинаты
 
Description The aim of the review is to present potentially negative effects of hyperoxia in various groups of critically ill patients, including those after cardiac arrest, brain injury or stroke, and in cases of sepsis. It was noted that in cases of these pathological processes and nosological forms there were evidences that hyperoxia could have a damaging effect, and that oxygen should be prescribed on an individual basis depending on the assessment of the current oxy- gen requirement. It has been established that hyperoxia commonly represent the last reserve to abrogate the progressive hypoxia. The mechanisms of adaptation of the body to hyperoxia are described and the possibility to reduce the toxic effects of oxygen with the aid of succinates is discussed. 
Цель обзора — представить потенциально негативные эффекты гипероксии у различных групп боль- ных, находящихся в критическом состоянии, в том числе после остановки сердца, черепно-мозговой трав- мы, инсульта, в случаях развития сепсиса. Приведены доказательства повреждающего эффекта гипероксии и необходимости индивидуального использования кислорода в соответствии с текущей потребностью при ряде патологических процессов и нозологических форм. Описаны механизмы адаптации организма к гипероксии и возможность уменьшения токсических эффектов кислорода с помощью сукцинатов. 
 
Publisher FSBI "SRIGR" RAMS
 
Contributor

 
Date 2017-06-30
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Рецензированная статья
 
Format application/pdf
 
Identifier http://www.reanimatology.com/rmt/article/view/1594
10.15360/1813-9779-2017-3-83-93
 
Source General Reanimatology; Том 13, № 3 (2017); 83-93
Общая реаниматология; Том 13, № 3 (2017); 83-93
2411-7110
1813-9779
10.15360/1813-9779-2017-3
 
Language rus
 
Relation http://www.reanimatology.com/rmt/article/view/1594/1096
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