Mechanical circulation support of the treatment for children with end-stage chronic heart failure
Russian Journal of Transplantology and Artificial Organs
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Title |
Mechanical circulation support of the treatment for children with end-stage chronic heart failure
Механическая поддержка кровообращения в лечении детей с терминальной сердечной недостаточностью |
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Creator |
S. Gautier V.; V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian Federation I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation G. Itkin P.; V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian Federation Moscow Institute of Physics and Technology (State University) O. Dmitrieva Yu.; V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian Federation V. Kozlov A.; V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian Federation С. Готье В.; ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России ФГАОУ ВО «Первый Московский государственный медицинский университет имени И.М. Сеченова» Минздрава России (Сеченовский университет) Г. Иткин П.; ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России Московский физико-технический институт (государственный университет) О. Дмитриева Ю.; ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России В. Козлов А.; ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России Московский физико-технический институт (государственный университет) |
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Subject |
heart transplantation; waiting list; congenital heart diseases; cardiomyopathy; pediatric mechanical circulatory support; extracorporeal membrane oxygenation; left ventricular bypass; biventricular bypass; pulsatile flow pumps; nonpulsatile flow pumps
трансплантация сердца;лист ожидания;врожденные пороки сердца;кардиомиопатия;педиатрическая механическая поддержка кровообращения;экстракорпоральная мембранная оксигенация;левожелудочковый обход;бивентрикулярный обход;насосы пульсирующего потока;насосы непульсирующего потока |
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Description |
Over the last decades mechanical circulation support has become one of the most effective treatment methods for patients with terminal heart failure. Unfortunately, in pediatrics this method is generally used on a short-term basis and includes, first of all, extracorporeal membranous oxygenation and left ventricular bypass by means of the extracorporeal centrifugal pumps. Nevertheless, using of these methods in children allowed considerably reducing mortality on the waiting list for heart transplant. Today, practically the only method of long term mechanical circulatory support in newborns and children at an early age being used is the system of paracorporeal artificial ventricles EXCOR, the usage of which results in larger problems of thrombosis. There is little clinical experience in using of the fully implanted systems developed for adults in older children. Therefore, as shown in the present review, the problem of creating long term circulatory support systems for newborns and younger children on the basis of the implanted pumps continues to be relevant.
Механическая поддержка кровообращения за последние десятилетия стала одним из наиболее эффективных средств лечения больных с терминальной сердечной недостаточностью. К сожалению, в педиатрии данный метод в основном используется для кратковременного подключения, и к нему относятся прежде всего экстракорпоральная мембранная оксигенация и левожелудочковый обход с помощью экстракорпорального подключения центробежных насосов. При этом применение данных методов у детей позволило значительно уменьшить смертность в листе ожидания на трансплантацию сердца. На сегодняшний день практически единственным методом длительной механической поддержки кровообращения у новорожденных и детей младшего возраста является система паракорпорального подключения искусственных желудочков EXCOR, применение которых связано с большими проблемами тромбоосложнений. Имеется относительно небольшой клинический опыт использования полностью имплантируемых систем, разработанных для взрослых, у детей старшего возраста. Поэтому, как показано в настоящем обзоре, задача создания систем длительной поддержки кровообращения для новорожденных и детей младшего возраста на основе имплантируемых насосов является актуальной. |
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Publisher |
Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation
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Contributor |
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Date |
2017-09-17
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Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion — — |
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Format |
application/pdf
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Identifier |
http://journal.transpl.ru/vtio/article/view/785
10.15825/1995-1191-2017-3-93-103 |
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Source |
Russian Journal of Transplantology and Artificial Organs; Том 19, № 3 (2017); 93-103
Вестник трансплантологии и искусственных органов; Том 19, № 3 (2017); 93-103 2412-6160 1995-1191 10.15825/1995-1191-2017-3 |
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Language |
rus
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Relation |
http://journal.transpl.ru/vtio/article/view/785/656
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