CLINICAL SIGNIFICANCE OF SERUM LEVELS OF CYTOKINES AND TOTAL IgE IN CHILDREN OF DIFFERENT AGE WITH SALMONELLOSIS
Medical Immunology
View Archive Info| Field | Value | |
| Title |
CLINICAL SIGNIFICANCE OF SERUM LEVELS OF CYTOKINES AND TOTAL IgE IN CHILDREN OF DIFFERENT AGE WITH SALMONELLOSIS
КЛИНИЧЕСКОЕ ЗНАЧЕНИЕ СЫВОРОТОЧНЫХ УРОВНЕЙ ЦИТОКИНОВ И ОБЩЕГО ИММУНОГЛОБУЛИНА E ПРИ САЛЬМОНЕЛЛЕЗЕ У ДЕТЕЙ РАЗНОГО ВОЗРАСТА |
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| Creator |
G. Zheleznikova F.; Institute of Children’s Infections, Saint Petersburg
M. Bechtereva K.; Institute of Children’s Infections, Saint Petersburg O. Volohova A.; Institute of Children’s Infections, Saint Petersburg N. Monahova E.; Institute of Children’s Infections, Saint Petersburg Г. Железникова Ф.; ФГБУ НИИ детских инфекций ФМБА России, Санкт-Петербург М. Бехтерева К.; ФГБУ НИИ детских инфекций ФМБА России, Санкт-Петербург О. Волохова А.; ФГБУ НИИ детских инфекций ФМБА России, Санкт-Петербург Н. Монахова Е.; ФГБУ НИИ детских инфекций ФМБА России, Санкт-Петербург |
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| Subject |
cytokines; total IgE; salmonellosis; children
цитокины; общий IgE; сальмонеллез; дети |
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| Description |
Abstract. The serum levels of cytokines and total IgE in 113 children with salmonellosis were tested in ELISA. It was established, that severe course of infection in chidren up to 4 years of age is associated with low level of IL-10, and after 4 years of age with IFNγ deficit. Low level of total IgE is the marker of severe salmonellosis too, particularly in children up to 4 years of age.
Резюме. У 113 детей с сальмонеллезом определили уровни цитокинов и общего IgE методом ИФА. Установлено, что тяжелая форма инфекции у детей младше 4 лет ассоциирована с низким уровнем IL-10, а старше 4 лет — с дефицитом IFNγ. Маркером тяжелой формы инфекции является также низкий уровень общего IgE, особенно у больных младшей группы. |
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| Publisher |
Publishing house of Saint Petersburg Pasteur Institute
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| Contributor |
—
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| Date |
2014-07-11
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| Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion — — |
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| Format |
application/pdf
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| Identifier |
http://iimmun.ru/index.php/iimm/article/view/176
10.15789/2220-7619-2013-3-279–284 |
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| Source |
Russian Journal of Infection and Immunity; Том 3, № 3 (2013); 279–284
Инфекция и иммунитет; Том 3, № 3 (2013); 279–284 2313-7398 2220-7619 10.15789/2220-7619-2013-3 |
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| Language |
rus
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| Relation |
http://iimmun.ru/index.php/iimm/article/view/176/175
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| Rights |
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