THE STUDY OF VIRUSES REPRODUCTION IN CELL CULTURES BY THE METHOD OF MATHEMATICAL MODELING
Medical Immunology
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Title |
THE STUDY OF VIRUSES REPRODUCTION IN CELL CULTURES BY THE METHOD OF MATHEMATICAL MODELING
ИССЛЕДОВАНИЕ РАЗМНОЖЕНИЯ ВИРУСОВ В КУЛЬТУРЕ КЛЕТОК МЕТОДОМ МАТЕМАТИЧЕСКОГО МОДЕЛИРОВАНИЯ |
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Creator |
N. Kontarov A.; Research Institute of Vaccines and Sera of I.I. Mechnikov RAMS, Moscow
S. Grishunina A.; Lomonosov Moscow State University, Moscow N. Balaev V.; Research Institute of Vaccines and Sera of I.I. Mechnikov RAMS, Moscow N. Yuminova V.; Research Institute of Vaccines and Sera of I.I. Mechnikov RAMS, Moscow V. Zverev V.; Research Institute of Vaccines and Sera of I.I. Mechnikov RAMS, Moscow Н. Контаров А.; ФГБУ НИИ вакцин и сывороток им. И.И. Мечникова РАМН, Москва С. Гришунина А.; ФГБУ ВПО Московский государственный университет им. М.В. Ломоносова, Москва Н. Балаев В.; ФГБУ НИИ вакцин и сывороток им. И.И. Мечникова РАМН, Москва Н. Юминова В.; ФГБУ НИИ вакцин и сывороток им. И.И. Мечникова РАМН, Москва В. Зверев В.; ФГБУ НИИ вакцин и сывороток им. И.И. Мечникова РАМН, Москва |
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Subject |
multiplication of the virus; cell culture; mathematical model Marchuk; a stable node
размножение вируса; культура клеток; математическая модель Марчука; устойчивый узел |
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Description |
Abstract. In the study the mathematical analysis of viruses reproduction in cell culture using the Marchuk’ mathematical model to predict reproduction of virus in one or another cell cultures has been conducted. The obtained theoretical results are corresponded to the experimental data on reproduction of rubella virus in cell cultures RK-13 and BHK-21. The sum of theoretical and experimental results can be used to select the optimal cell cultures for virus cumulation.
Резюме. В работе проведен математический анализ размножения вирусов в культуре клеток с использованием математической модели Марчука с целью осуществления прогноза размножения вируса в той или иной культуре клеток. Полученные теоретические результаты хорошо согласуются с экспериментальными данными на примере размножения вируса краснухи в культуре клеток RK-13 и BHK-21. Совокупность полученных теоретических и экспериментальных результатов можно применять для выбора оптимальной культуры клеток для размножения вирусов. |
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Publisher |
Publishing house of Saint Petersburg Pasteur Institute
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Contributor |
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Date |
2014-07-09
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Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion — — |
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Format |
application/pdf
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Identifier |
http://iimmun.ru/index.php/iimm/article/view/150
10.15789/2220-7619-2013-4-376-378 |
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Source |
Russian Journal of Infection and Immunity; Том 3, № 4 (2013); 376-378
Инфекция и иммунитет; Том 3, № 4 (2013); 376-378 2313-7398 2220-7619 10.15789/2220-7619-2013-4 |
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Language |
rus
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Relation |
http://iimmun.ru/index.php/iimm/article/view/150/149
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Rights |
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