AUTOREACTIVE ANTIBODIES IN A HEALTHY HUMAN AND IN PATIENTS WITH VIRAL INFECTIONS
Medical Immunology
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Title |
AUTOREACTIVE ANTIBODIES IN A HEALTHY HUMAN AND IN PATIENTS WITH VIRAL INFECTIONS
АУТОРЕАКТИВНЫЕ АНТИТЕЛА В НОРМЕ И ПРИ ВИРУСНЫХ ИНФЕКЦИЯХ |
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Creator |
V. Krivitskaya Z.; Research Institute of Influenza, Ministry of Health of the Russian Federation, St. Petersburg
В. Кривицкая З.; ФГБУ НИИ гриппа МЗ РФ, Санкт-Петербург |
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Subject |
autoreactive antibodies; natural antibodies; polyspecificity; innate immunity; adaptive immune response; viral infections; antiviral vaccination
аутореактивные антитела; нормальные антитела; полиспецифичность, врожденный иммунитет; адаптивный иммунный ответ; вирусные инфекции; противовирусная вакцинация |
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Description |
Abstract. This brief review presents the data obtained during the last two decades which allow to create a new view on autoimmunity. Regulatory and protective characteristics of autoreactive natural antibodies and their role in development of effective adaptive antiviral immune response are discussed. The article considers the problem of possible autoimmune complications due to some viral infections and antiviral vaccination.
Резюме. В кратком обзоре литературы представлены данные последних двух десятилетий, позволившие сформировать новый взгляд на роль аутоиммунных процессов в жизнедеятельности организма человека. Рассмотрен вопрос о регуляторных и протективных свойствах аутореактивных нормальных антител, а также их роли в формировании эффективного адаптивного противовирусного иммунного ответа. Обсуждается проблема возможных аутоиммунных осложнений некоторых вирусных заболеваний и противовирусной вакцинации. |
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Publisher |
Publishing house of Saint Petersburg Pasteur Institute
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Contributor |
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Date |
2014-07-08
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Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion — — |
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Format |
application/pdf
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Identifier |
http://iimmun.ru/index.php/iimm/article/view/138
10.15789/2220-7619-2013-4-301-310 |
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Source |
Russian Journal of Infection and Immunity; Том 3, № 4 (2013); 301-310
Инфекция и иммунитет; Том 3, № 4 (2013); 301-310 2313-7398 2220-7619 10.15789/2220-7619-2013-4 |
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Language |
rus
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Relation |
http://iimmun.ru/index.php/iimm/article/view/138/137
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Rights |
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