Diabetic retinopathy in type two diabetic patients: Epidemiology and modern view on the pathogenesis. Review
Ophthalmology
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| Title |
Diabetic retinopathy in type two diabetic patients: Epidemiology and modern view on the pathogenesis. Review
Диабетическая ретинопатия у больных сахарным диабетом второго типа. Эпидемиология, современный взгляд на патогенез. Обзор |
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| Creator |
I. Vorobieva V.
D. Merkushenkova A. И. Воробьева В.; Кафедра офтальмологии ГБОУ ДПО «Российская медицинская академия последипломного образования Минздравсоцразвития России», Москва Д. Меркушенкова А.; Кафедра офтальмологии ГБОУ ДПО «Российская медицинская академия последипломного образования Минздравсоцразвития России», Москва |
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| Subject |
diabetic retinopathy; diabetic macular edema; diabetes mellitus type two; pathogenesis; angiogenesis; VEGF; PEDF
диабетическая ретинопатия; диабетический макулярный отек; сахарный диабет второго типа; патогенез; фактор роста эндотелия сосудов; ангиогенез |
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| Description |
Development of late microvascular complications — diabetic retinopathy, nephropathy and neuropathy — in type 2 diabetic pa- tients is associated with higher invalidization risk and lethality. Diabetic retinopathy is the leading cause of blindness in people of work- ing age in developed countries. Classical approach to diabetic retinal damage pathogenesis is widened and considered at the molecular level in terms of cell interactions during angiogenesis. In this literal review the actual epidemiological data is presented along with therole of angiogenic factors in diabetic retinopathy and maculopathy pathogenesis.
Диабетическая ретинопатия является ведущей причиной слепоты среди лиц трудоспособного возраста в развитых стра- нах. Классические представления о патогенезе диабетического поражения сетчатки на современном этапе расширяются за счет изучения его молекулярных основ с позиции межклеточных взаимодействий в рамках процесса ангиогенеза. В обзо- ре представлены актуальные эпидемиологические данные о распространенности диабетической ретинопатии и макулярного отека, современный взгляд на роль ангиогенных факторов в патогенезе диабетической ретинопатии и макулопатии. |
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| Publisher |
Ophthalmology
Офтальмология |
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| Contributor |
—
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| Date |
2014-07-16
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| Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion — — |
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| Format |
application/pdf
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| Identifier |
http://www.ophthalmojournal.com/index.php/opht/article/view/168
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| Source |
Ophthalmology; Том 9, № 4 (2012); 18-21
Офтальмология; Том 9, № 4 (2012); 18-21 1816-5095 |
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| Language |
rus
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| Relation |
http://www.ophthalmojournal.com/index.php/opht/article/view/168/159
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| Rights |
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