ADJUVANT RADIOTHERAPY AFTER RADICAL PROSTATECTOMY
Oncourology
View Archive Info| Field | Value | |
| Title |
ADJUVANT RADIOTHERAPY AFTER RADICAL PROSTATECTOMY
АДЪЮВАНТНАЯ ЛУЧЕВАЯ ТЕРАПИЯ ПОСЛЕ РАДИКАЛЬНОЙ ПРОСТАТЭКТОМИИ |
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| Creator |
O. Karyakin В.; Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk
А. Карякин О.; МРНЦ РАМН, Обнинск |
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| Subject |
prostate cancer; radical prostatectomy; prostate-specific antigen; postoperative radiotherapy
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| Description |
The rate of a biochemical and clinical recurrence at stage T1-T2 is 25-35%. Experience with surgical treatment for stage T3 cancer shows that 33.5-66% of patients a positive surgical margin and 7.9-49% of patients have a metastatic lymph node lesion. One of the further treatment options is teleradiotherapy (TRT) for a removed prostate area, which is performed immediately after surgical treatment and in case of a biochemical or clinical recurrence both alone and in combination with others treatments (hormonal therapy, chemotherapy, etc.). The paper presents the data of basic international studies of adjuvant radiotherapy after radical prostatectomy. The results of the therapy depend on the baseline level of prostate-specific antigen, the interval between the start of radiotherapy and surgery, the stage of the disease, and other prognostic factors. A number of investigations of the use of TRT, hormonal therapy, chemotherapy, and their combinations in the adjuvant mode are ongoing. This will provide answers to what combinations of adjuvant therapy may increase survival and improve quality of life in patients with prostate cancer.
The rate of a biochemical and clinical recurrence at stage T1-T2 is 25-35%. Experience with surgical treatment for stage T3 cancer shows that 33.5-66% of patients a positive surgical margin and 7.9-49% of patients have a metastatic lymph node lesion. One of the further treatment options is teleradiotherapy (TRT) for a removed prostate area, which is performed immediately after surgical treatment and in case of a biochemical or clinical recurrence both alone and in combination with others treatments (hormonal therapy, chemotherapy, etc.). The paper presents the data of basic international studies of adjuvant radiotherapy after radical prostatectomy. The results of the therapy depend on the baseline level of prostate-specific antigen, the interval between the start of radiotherapy and surgery, the stage of the disease, and other prognostic factors. A number of investigations of the use of TRT, hormonal therapy, chemotherapy, and their combinations in the adjuvant mode are ongoing. This will provide answers to what combinations of adjuvant therapy may increase survival and improve quality of life in patients with prostate cancer. |
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| Publisher |
"PH "ABV-Press"", LLC
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| Contributor |
—
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| Date |
2014-07-24
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| Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion — — |
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| Format |
application/pdf
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| Identifier |
http://oncourology.abvpress.ru/index.php/oncur/article/view/29
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| Source |
Oncourology; № 1 (2010); 65-69
Онкоурология; № 1 (2010); 65-69 1726-9776 |
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| Language |
rus
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| Relation |
http://oncourology.abvpress.ru/index.php/oncur/article/view/29/44
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| Rights |
Authors who publish with this journal agree to the following terms:Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
Авторы, публикующие в данном журнале, соглашаются со следующим:Авторы сохраняют за собой авторские права на работу и предоставляют журналу право первой публикации работы на условиях лицензии Creative Commons Attribution License, которая позволяет другим распространять данную работу с обязательным сохранением ссылок на авторов оригинальной работы и оригинальную публикацию в этом журнале.Авторы сохраняют право заключать отдельные контрактные договоронности, касающиеся не-эксклюзивного распространения версии работы в опубликованном здесь виде (например, размещение ее в институтском хранилище, публикацию в книге), со ссылкой на ее оригинальную публикацию в этом журнале.Авторы имеют право размещать их работу в сети Интернет (например в институтском хранилище или персональном сайте) до и во время процесса рассмотрения ее данным журналом, так как это может привести к продуктивному обсуждению и большему количеству ссылок на данную работу (См. The Effect of Open Access). |
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